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Antidepressants Linked to Birth Defect

uk canada goose Sept. 24, 2009 New research adds to the evidence that Canada Goose online babies canadian goose jacket born to women who take antidepressants during pregnancy have a small increased risk for a specific canada goose clearance sale heart defect. uk canada goose

Canada Goose Outlet The Danish study also shows that the risk is greatest when moms to be take more than one selective serotonin reuptake inhibitor (SSRI) antidepressant or switch SSRIs early in pregnancy. Canada Goose Outlet

SSRIs such as Prozac, Paxil, Zoloft, Celexa and Lexapro are the most widely prescribed drugs for depression; millions of women take them during pregnancy.

canada goose coats The new study shows the overall risk for congenital heart problems associated with SSRI to canada goose store be quite low. canada goose coats

Canada Goose Online But babies born to women who had filled prescriptions for more than one SSRI had a fourfold increase in septal heart defects a malformation of the wall that divides the left and right sides of the heart. Canada Goose Online

canada goose Unclear if All SSRIs Carry Risk canada goose

canadian goose jacket The finding will no doubt add to the confusion surrounding the safety of specific SSRIs during pregnancy. canadian goose jacket

buy canada goose jacket In 2005, based on the research at the time, the FDA singled out the drug Paxil, warning that its use was associated with an increased risk for heart defect. buy canada goose jacket

cheap Canada Goose It has since become common practice for doctors to switch women taking Paxil to another SSRI when they canada goose clearance become pregnant or are considering pregnancy. cheap Canada Goose

But more recent studies suggest that women who take Paxil have no greater canada goose black friday sale risk for delivering babies with the heart defect than women who take other antidepressants.

In the Danish study, use of Celexa and Zoloft early in pregnancy was associated with a small increased risk for the heart defect, but no association canada goose coats was seen in women who took Paxil or Prozac.

Canada Goose online The study compared the incidence of birth defects among Canada Goose Outlet babies born to Danish women who did and did not take SSRIs during their first trimester. The study included more than 400,000 children born between 1996 and 2003. Canada Goose online

canada goose uk black friday Septal heart defects occurred in 0.5% of children born to mothers who did not take antidepressants and 0.9% of children born to mothers who did. SSRI use was not linked to any other major birth defect. canada goose uk black friday

canada goose uk shop “The bottom line buy canada goose jacket cheap is the risk associated with SSRI use appears to Canada Goose Parka be very small, and this has to be balanced against the very real risk associated with having untreated depression during pregnancy,” study researcher Lars H. Pedersen of Aarhus University tells WebMD. canada goose uk shop

Larger Studies Needed

Canada Goose Jackets Pedersen says much larger studies are needed to determine whether any one SSRI is safer or less safe than any other during pregnancy. Canada Goose Jackets

Canada Goose Coats On Sale In an editorial published with the study Friday in BMJ Online First, birth defects researcher Christina Chambers, PhD, agrees that larger studies are needed. Canada Goose Coats On Sale

Canada Goose Parka Chambers is an epidemiologist and associate professor at the University of California, San Diego School of Medicine. Canada Goose Parka

buy canada goose jacket cheap “If an increased risk for major congenital malformations does exist, this study and others suggest that the absolute risk for the individual pregnant woman cheap Canada Goose https://www.winterdownparkas.com is very low,” she writes. teamed up to buy canada goose jacket issue guidelines for treating depression during pregnancy. buy canada goose jacket cheap

uk canada goose outlet The joint statement from the American College of Obstetricians and Gynecologists (ACOG) and the American canada goose coats on sale Psychiatric Association (APA) recommended that: uk canada goose outlet

canada goose clearance Women who canada goose experience psychotic episodes, have bipolar disorder, or those who are canada goose deals suicidal or have a history of suicide attempts should not be taken off antidepressants. canada goose clearance

canada goose clearance sale Women with mild depression and those who have had few symptoms for six months or longer can consider gradually reducing their drug doses or stopping drugs altogether under the close supervision of their prescribing doctor. canada goose clearance sale

Canada Goose sale Psychotherapy and other treatments may be an appropriate alternative to drugs during pregnancy for some, but not all, women with depression. Canada Goose sale

canada goose factory sale Chambers tells WebMD that the joint ACOG/APA guidelines should help women and their doctors understand their options. canada goose factory sale

“Every pregnant woman has about a 3% risk canada goose outlet of having a baby with a birth defect,” she says. “If there is a risk associated with SSRI use it is very Canada Goose sale small over and above this baseline risk.” Canada Goose Jackets.

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